Description

(R)-2-(4-Benzylpiperazin-2-Yl)Ethanol-2Hcl is a high-purity chiral piperazine derivative supplied as a dihydrochloride salt. This compound serves as a critical pharmaceutical intermediate and building block for the synthesis of complex bioactive molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and receptor-targeted drugs.
• Medicinal Chemistry Research: Used in drug discovery and development for structure-activity relationship (SAR) studies and lead optimization.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in regulatory filings.
• Bioconjugation & Probe Development: Utilized for modifying biomolecules or creating labeled probes for biochemical and pharmacological assays.

Basic Information

Product Name	(R)-2-(4-Benzylpiperazin-2-Yl)Ethanol-2Hcl
CAS No.	857334-79-3
Molecular Formula	C₁₃H₂₂Cl₂N₂O
Molecular Weight	293.23 g/mol
Synonyms	(R)-2-(4-Benzyl-2-piperazinyl)ethanol dihydrochloride; (R)-2-(4-Benzylpiperazin-2-yl)ethan-1-ol dihydrochloride; 2-[(2R)-4-Benzyl-2-piperazinyl]ethanol dihydrochloride; (R)-4-Benzyl-2-(2-hydroxyethyl)piperazine dihydrochloride; (R)-2-(4-Bn-piperazin-2-yl)ethanol 2HCl; (R)-2-Hydroxyethyl-4-benzylpiperazine dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-(4-Benzylpiperazin-2-Yl)Ethanol-2Hcl is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, chiral HPLC) are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.