Description

Piperidine-2-Carboxamide Hydrochloride is a high-purity organic salt derivative of pipecolic acid, serving as a critical chiral building block and intermediate in advanced chemical synthesis. Its value lies in providing a structurally defined, nitrogen-containing scaffold essential for constructing complex molecules with high stereochemical fidelity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides that require specific stereochemistry for optimal biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Research: Incorporated into the backbone of peptide analogs to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a defined piperidine carboxylic acid derivative.

Basic Information

Product Name	Piperidine-2-Carboxamide Hydrochloride
CAS No.	857242-96-7
Molecular Formula	C6H13ClN2O
Molecular Weight	164.63 g/mol
Synonyms	2-Piperidinecarboxamide hydrochloride; L-Pipecolic acid amide hydrochloride; (S)-Piperidine-2-carboxamide hydrochloride; Pipecolamide hydrochloride; 2-Aminocarbonylpiperidine hydrochloride; Amide of L-pipecolic acid hydrochloride; (2S)-Piperidine-2-carboxamide monohydrochloride
EINECS	Contact for details

Quality Control

Every batch of Piperidine-2-Carboxamide Hydrochloride is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications that are aligned with pharmaceutical intermediate standards. A detailed Certificate of Analysis (COA) providing purity, chiral purity, and impurity profile data is supplied with each shipment to guarantee traceability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation and clumping. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.