Description

1-(Toluene-4-Sulfonyl)-Piperazine Hydrochloride is a high-purity, functionalized piperazine derivative widely used as a key synthetic intermediate in advanced organic chemistry. This compound is critical for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality building blocks for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging the piperazine scaffold for biological activity.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D for exploring new chemical reactions and creating compound libraries for high-throughput screening.
• Ligand and Catalyst Preparation: Employed in the preparation of specialized ligands for metal-catalyzed reactions or as a precursor for functionalized catalysts.
• Material Science: Potential use in the synthesis of advanced polymers or functional materials requiring specific sulfonamide or amine functionalities.

Basic Information

Product Name	1-(Toluene-4-Sulfonyl)-Piperazine Hydrochloride
CAS No.	856843-84-0
Molecular Formula	C11H17ClN2O2S
Molecular Weight	276.78 g/mol
Synonyms	1-(4-Toluenesulfonyl)piperazine hydrochloride; 1-Tosylpiperazine hydrochloride; N-(p-Tolylsulfonyl)piperazine hydrochloride; Piperazine, 1-(4-methylbenzenesulfonyl)-, hydrochloride; 4-Methyl-N-(piperazin-1-ylsulfonyl)benzenamine hydrochloride; Tosylpiperazine HCl; 1-(p-Toluenesulfonyl)piperazine HCl
EINECS	Contact for details

Quality Control

Our 1-(Toluene-4-Sulfonyl)-Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.