Description

(2,2-Dimethyl-3-Oxo-Piperazin-1-Yl)-Acetic Acid is a high-purity pharmaceutical intermediate and building block of significant commercial importance. Its value lies in its role as a key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic chemistry. This compound is essential for research and manufacturing organizations in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop new drug candidates or produce specialized compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly protease inhibitors and other enzyme-targeted therapies.
• API Synthesis: Used in the research, development, and commercial-scale production of Active Pharmaceutical Ingredients (APIs) with complex piperazine-based structures.
• Bioconjugation & Linker Chemistry: Serves as a functionalized linker molecule for bioconjugation applications in antibody-drug conjugates (ADCs) and other targeted therapies.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and combinatorial chemistry libraries in drug discovery.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, catalysts, and advanced materials requiring precise molecular architecture.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis projects and process development.

Basic Information

Product Name	(2,2-Dimethyl-3-Oxo-Piperazin-1-Yl)-Acetic Acid
CAS No.	856437-83-7
Molecular Formula	C8H14N2O3
Molecular Weight	186.21 g/mol
Synonyms	1-(Carboxymethyl)-2,2-dimethyl-3-oxopiperazine; 2,2-Dimethyl-3-oxo-1-piperazineacetic Acid; (2,2-Dimethyl-3-oxopiperazin-1-yl)acetic Acid; 1-Piperazineacetic acid, 2,2-dimethyl-3-oxo-; Acetic acid, (2,2-dimethyl-3-oxo-1-piperazinyl)-; 856437-83-7; 2,2-Dimethyl-3-oxopiperazine-1-acetic acid
EINECS	Contact for details

Quality Control

Our (2,2-Dimethyl-3-Oxo-Piperazin-1-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.