Description

Ethaverine Hydrobromide is a pharmaceutically active salt form of the vasodilator papaverine derivative. This compound is valued for its enhanced solubility and stability profile compared to other salt forms, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily required by manufacturers in the life sciences sector for the research, development, and production of specialized cardiovascular and antispasmodic medications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of high-purity active pharmaceutical ingredients (APIs) targeting smooth muscle relaxation.
• Vasodilator Research: Used in preclinical and clinical research for developing new treatments for cerebral and peripheral vascular insufficiency.
• Antispasmodic Drug Development: Serves as a precursor in formulating medications for conditions involving smooth muscle spasms, such as certain gastrointestinal and urinary tract disorders.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development, validation, and impurity profiling.
• Chemical Synthesis: Utilized in organic chemistry research for the preparation of novel papaverine analogues with potential therapeutic activity.

Basic Information

Product Name	Ethaverine Hydrobromide
CAS No.	855701-63-2
Molecular Formula	C₂₅H₃₂BrNO₄
Molecular Weight	490.43 g/mol
Synonyms	Ethylpapaverine Hydrobromide; Ethaverin Hydrobromide; 6,7-Diethoxy-1-(3,4-diethoxybenzyl)isoquinoline Hydrobromide; NSC 289491; 1-(3,4-Diethoxybenzyl)-6,7-diethoxyisoquinoline Hydrobromide; Papaverine Ethyl Derivative Hydrobromide
EINECS	Contact for details

Quality Control

Our Ethaverine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.