Description

Dl-Phenylephrine Hydrochloride CAS NO 154-86-9 is a synthetic sympathomimetic amine, a racemic mixture of the D- and L-isomers of phenylephrine. This compound is a critical pharmaceutical intermediate and active ingredient valued for its vasoconstrictive properties. It is primarily required by manufacturers in the pharmaceutical, research, and fine chemical synthesis sectors for developing nasal decongestants, ophthalmic solutions, and other adrenergic agents.

Application

• Pharmaceutical Active Ingredient (API): Key component in the formulation of nasal decongestant sprays and drops.
• Ophthalmic Solutions: Used in eye drops to induce mydriasis (pupil dilation) for diagnostic procedures.
• Research & Development: Serves as a standard reference compound and intermediate in pharmacological and biochemical research.
• Vasopressor Agent: Employed in certain medicinal formulations to manage hypotension.
• Fine Chemical Synthesis: Acts as a chiral building block for the synthesis of more complex adrenergic compounds.
• Analytical Standards: Used as a high-purity standard in HPLC and other analytical methods for quality control.

Basic Information

Product Name	Dl-Phenylephrine Hydrochloride
CAS No.	154-86-9
Molecular Formula	C9H13NO2 • HCl
Molecular Weight	203.67 g/mol
Synonyms	(±)-Phenylephrine Hydrochloride; DL-m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol hydrochloride; Racemic Phenylephrine HCl; 3-[(1RS)-1-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride; m-Hydroxynorephedrine hydrochloride; Neo-Synephrine (racemic form); Adria; Metaoxedrine
EINECS	205-840-8

Quality Control

Our Dl-Phenylephrine Hydrochloride is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing specifications such as assay, optical rotation, and impurity profiles are available upon request. We can supply material compliant with various pharmacopeial monographs, including USP and EP, based on customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Optical Rotation	-0.10° to +0.10° (c=2 in H2O)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.