Description

Pimefylline is a synthetic xanthine derivative with significant pharmacological activity, primarily recognized for its bronchodilatory and anti-inflammatory properties. This compound is a key intermediate in the synthesis of advanced pharmaceutical agents targeting respiratory conditions. It is essential for manufacturers and research institutions in the pharmaceutical and life sciences sectors requiring high-purity building blocks for drug development and production.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of active pharmaceutical ingredients (APIs) for respiratory medications.
• Bronchodilator Research: Serves as a reference standard and key material in preclinical and clinical research for asthma and chronic obstructive pulmonary disease (COPD) therapeutics.
• Anti-inflammatory Agent Development: Utilized in R&D programs focused on developing new anti-inflammatory drugs due to its mechanism of action as a phosphodiesterase (PDE) inhibitor.
• Biochemical Research: Used in laboratory studies to investigate cellular signaling pathways, particularly those involving cyclic nucleotides.
• Veterinary Pharmaceuticals: Potential application in the formulation of veterinary drugs for treating respiratory ailments in animals.

Basic Information

Product Name	Pimefylline
CAS No.	10001-43-1
Molecular Formula	C₁₀H₁₄N₄O₂
Molecular Weight	222.25 g/mol
Synonyms	Pimefylline; 1,3-Dimethyl-7-(2-hydroxypropyl)-3,7-dihydro-1H-purine-2,6-dione; 7-(2-Hydroxypropyl)theophylline; Proxyphylline; Monophylline; Oxypropyltheophylline; Theo-Oxypropyl; Theophylline, 7-(2-hydroxypropyl)-
EINECS	233-007-5

Quality Control

Our Pimefylline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, NMR) to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) documenting full compliance are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.