Description

1-(2-Chloro-Pyridin-4-Yl)-Piperazine is a high-value pharmaceutical intermediate and versatile chemical building block. This compound is crucial for the synthesis of complex molecules, particularly in medicinal chemistry for developing new active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for its role in creating novel compounds with potential therapeutic or pesticidal activity.

Application

• Key intermediate in the synthesis of pharmaceutical candidates, particularly kinase inhibitors and central nervous system (CNS) active drugs.
• Building block for advanced agrochemicals, including the development of new herbicides and insecticides.
• Precursor in medicinal chemistry research for structure-activity relationship (SAR) studies and lead optimization.
• Used in the preparation of complex heterocyclic compounds for material science applications.
• Essential reagent in custom synthesis and contract manufacturing for the life sciences industry.

Basic Information

Product Name	1-(2-Chloro-Pyridin-4-Yl)-Piperazine
CAS No.	854159-45-8
Molecular Formula	C9H12ClN3
Molecular Weight	197.66 g/mol
Synonyms	1-(2-Chloropyridin-4-yl)piperazine; 4-(2-Chloropyridin-4-yl)piperazine; 2-Chloro-4-piperazin-1-ylpyridine; 1-(2-Chloro-4-pyridinyl)piperazine; Piperazine, 1-(2-chloro-4-pyridinyl)-; 854159-45-8
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-Pyridin-4-Yl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.