Description

2-(4-Piperazinyl)-8-Phenyl-4H-1-Benzopyran-4-One Dihydrochloride is a high-purity, chemically defined organic salt with significant utility in advanced research and development. This compound serves as a critical pharmacological reference standard and a key synthetic intermediate for the development of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as an analytical standard for quality control, method development, and validation in API manufacturing.
• Biochemical Research: Employed in in-vitro assays to study enzyme inhibition, receptor binding, and other biological mechanisms.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological investigations.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services.

Basic Information

Item	Details
Product Name	2-(4-Piperazinyl)-8-Phenyl-4H-1-Benzopyran-4-One Dihydrochloride
CAS No.	854127-90-5
Molecular Formula	C19H19N3O2·2HCl
Molecular Weight	402.29 g/mol (free base: 321.38 g/mol)
Synonyms	8-Phenyl-2-(piperazin-1-yl)-4H-chromen-4-one dihydrochloride; 2-(1-Piperazinyl)-8-phenyl-4H-1-benzopyran-4-one dihydrochloride; 8-Phenyl-2-piperazinyl-4H-chromen-4-one dihydrochloride; Chromone derivative; Flavone derivative; Piperazinyl chromone salt
EINECS	Contact for details

Quality Control

Our 2-(4-Piperazinyl)-8-Phenyl-4H-1-Benzopyran-4-One Dihydrochloride is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.