Description

2,4-Thiazolidinedione, 5-[[5-[6-(4-Acetyl-1-Piperazinyl)-3-Nitro-2-Pyridinyl]-2-Fluorophenyl]Methylene]- is a high-purity, complex heterocyclic compound designed for advanced research and development. This molecule is of significant interest as a key synthetic intermediate or a potential pharmacologically active scaffold in medicinal chemistry programs. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing novel therapeutic agents. The compound's specific structure makes it valuable for targeted synthesis and biological screening.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or a lead compound in the synthesis of novel drug candidates, particularly for metabolic and oncological targets.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and molecular optimization to enhance potency, selectivity, and pharmacokinetic properties.
• Biochemical Research: Employed as a tool compound in enzymatic assays and cellular studies to investigate specific biological pathways and mechanisms of action.
• Fine Chemical Synthesis: Acts as a specialized building block for the multi-step synthesis of complex, high-value organic molecules in contract manufacturing.
• Reference Standard: Used as an analytical standard for quality control, method development, and regulatory submissions in pharmaceutical analysis.

Basic Information

Product Name	2,4-Thiazolidinedione, 5-[[5-[6-(4-Acetyl-1-Piperazinyl)-3-Nitro-2-Pyridinyl]-2-Fluorophenyl]Methylene]-
CAS No.	853953-65-8
Molecular Formula	C23H20FN5O5S
Molecular Weight	489.50 g/mol
Synonyms	5-[[5-[6-(4-Acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-2,4-thiazolidinedione; 5-((5-(6-(4-Acetylpiperazin-1-yl)-3-nitropyridin-2-yl)-2-fluorobenzylidene)thiazolidine-2,4-dione; TZD Derivative 853953-65-8; (5Z)-5-[[5-[6-(4-Acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-2,4-thiazolidinedione; 853953-65-8; 5-((5-(6-(4-Acetylpiperazin-1-yl)-3-nitropyridin-2-yl)-2-fluorobenzylidene)-1,3-thiazolidine-2,4-dione
EINECS	Contact for details

Quality Control

Our 2,4-Thiazolidinedione derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.