Description

1-(3,4-Difluoro-Phenyl)-Piperazine Hydrochloride is a high-purity, functionalized piperazine derivative used as a critical building block in advanced organic synthesis. This compound is essential for pharmaceutical research and development, particularly in the creation of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily utilized by R&D chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with neurological or psychiatric activity.
• Chemical Research & Development: Serves as a versatile building block for constructing complex molecular architectures in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging the difluorophenyl moiety for enhanced biological activity and stability.
• Ligand and Catalyst Development: The piperazine core can be functionalized to create novel ligands for catalysis or metal complexation.
• Material Science Research: Potential monomer or additive in the development of specialty polymers with specific electronic or physical properties.

Basic Information

Product Name	1-(3,4-Difluoro-Phenyl)-Piperazine Hydrochloride
CAS No.	853745-58-1
Molecular Formula	C10H13ClF2N2
Molecular Weight	234.67 g/mol
Synonyms	1-(3,4-Difluorophenyl)piperazine hydrochloride; 3,4-Difluoro-1-(piperazin-1-yl)benzene hydrochloride; 1-(3,4-Difluorophenyl)piperazine HCl; 853745-58-1; 3,4-Difluorophenylpiperazine hydrochloride; N-(3,4-Difluorophenyl)piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3,4-Difluoro-Phenyl)-Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.