Description

R-2-Isobutyl-Piperazine-2Hcl is a high-purity chiral piperazine derivative, supplied as a dihydrochloride salt. This compound serves as a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and other specialty molecules.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• API Development: Used in research and process development for constructing complex molecular architectures in active pharmaceutical ingredients.
• Chemical Research: Valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.
• Agrochemical Synthesis: Potential intermediate in the development of advanced, chiral agrochemicals and plant protection agents.

Basic Information

Product Name	R-2-Isobutyl-Piperazine-2Hcl
CAS No.	853730-57-1
Molecular Formula	C8H20Cl2N2
Molecular Weight	215.16 g/mol
Synonyms	(R)-2-Isobutylpiperazine Dihydrochloride; (R)-2-(2-Methylpropyl)piperazine Dihydrochloride; (R)-2-Isobutylpiperazine Hydrochloride (1:2); (R)-2-(Isobutyl)piperazine Dihydrochloride; (R)-2-(2-Methylpropyl)-1,4-diazacyclohexane Dihydrochloride; (R)-2-Isobutyl-piperazine-2HCl; R-2-Isobutylpiperazine 2HCl
EINECS	Contact for details

Quality Control

Our R-2-Isobutyl-Piperazine-2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and residual solvent levels are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.