Description

(4-Fluorophenyl)(1-Piperazinyl)Acetic Acid Dihydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its dihydrochloride salt form, which enhances stability and handling properties. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of bioactive molecules, particularly those targeting central nervous system receptors. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, including potential antipsychotics and antidepressants.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) research.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Tool Compound: Employed in vitro to study receptor-ligand interactions and signal transduction pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry Development: Utilized in scaling up synthetic routes for Active Pharmaceutical Ingredient (API) manufacturing.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and pharmacology projects.

Basic Information

Product Name	(4-Fluorophenyl)(1-Piperazinyl)Acetic Acid Dihydrochloride
CAS No.	853681-12-6
Molecular Formula	C12H16F N3O2 • 2HCl
Molecular Weight	338.19 g/mol (Free base: 265.28 g/mol)
Synonyms	2-(4-Fluorophenyl)-2-(piperazin-1-yl)acetic acid dihydrochloride; 1-[(4-Fluorophenyl)(carboxy)methyl]piperazine dihydrochloride; 4-Fluorophenyl(piperazin-1-yl)acetic acid dihydrochloride; (4-Fluorophenyl)(piperazinyl)acetic acid HCl salt; FPPA dihydrochloride; NSC 405124 (dihydrochloride)
EINECS	Contact for details

Quality Control

Our (4-Fluorophenyl)(1-Piperazinyl)Acetic Acid Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.