Description

4-(1-Piperazinyl)-1H-Pyrazolo[3,4-D]Pyrimidine Dihydrochloride is a high-purity, heterocyclic organic compound supplied as a dihydrochloride salt. This advanced pharmaceutical intermediate is critical for research and development in medicinal chemistry, offering a versatile scaffold for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro to study enzyme inhibition mechanisms and cellular signaling pathways.
• Preclinical Development: Employed in the scale-up synthesis of candidate drug molecules for toxicology and early-phase clinical studies.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for client-specific projects.

Basic Information

Product Name	4-(1-Piperazinyl)-1H-Pyrazolo[3,4-D]Pyrimidine Dihydrochloride
CAS No.	853680-94-1
Molecular Formula	C9H14Cl2N6
Molecular Weight	277.16 g/mol
Synonyms	4-Piperazin-1-yl-1H-pyrazolo[3,4-d]pyrimidine dihydrochloride; 1H-Pyrazolo[3,4-d]pyrimidine, 4-(1-piperazinyl)-, dihydrochloride; PP1 Analog Dihydrochloride; Pyrazolopyrimidine-piperazine dihydrochloride; 4-(Piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine dihydrochloride; CAS 853680-94-1
EINECS	Contact for details

Quality Control

Our 4-(1-Piperazinyl)-1H-Pyrazolo[3,4-D]Pyrimidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.