Description

1-[(3-Chloro-4-Fluorophenyl)Sulfonyl]Piperazine is a high-purity, specialized sulfonamide derivative of piperazine, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a halogenated phenylsulfonyl group, makes it a valuable intermediate for constructing complex molecules with targeted biological or material properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic system.
• Chemical Research & Development: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, ligands for catalysis, or advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and APIs.

Basic Information

Product Name	1-[(3-Chloro-4-Fluorophenyl)Sulfonyl]Piperazine
CAS No.	852388-67-1
Molecular Formula	C11H12ClFN2O2S
Molecular Weight	290.74 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)sulfonylpiperazine; 1-(3-Chloro-4-fluorobenzenesulfonyl)piperazine; 3-Chloro-4-fluoro-N-piperazin-1-ylbenzenesulfonamide; Piperazine, 1-[(3-chloro-4-fluorophenyl)sulfonyl]-; 852388-67-1; 1-(3-Chloro-4-fluorophenylsulfonyl)piperazine; Benzenesulfonamide, 3-chloro-4-fluoro-N-1-piperazinyl-
EINECS	Contact for details

Quality Control

Our production of 1-[(3-Chloro-4-Fluorophenyl)Sulfonyl]Piperazine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.