Description

4-Methyl-Piperazine-1,3-Dicarboxylic Acid 1-tert-Butyl Ester is a high-value, protected piperazine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the tert-butyl ester group, which provides excellent stability and selectivity during complex multi-step synthesis, particularly in the construction of nitrogen-containing heterocycles. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries who require high-purity building blocks for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific piperazine-based scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and conformationally restricted mimetics for biochemical studies.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds for clients.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Methyl-Piperazine-1,3-Dicarboxylic Acid 1-tert-Butyl Ester
CAS No.	851882-93-4
Molecular Formula	C11H20N2O4
Molecular Weight	244.29 g/mol
Synonyms	1-(tert-Butyl) 3-methyl 4-methylpiperazine-1,3-dicarboxylate; 4-Methylpiperazine-1,3-dicarboxylic acid 1-tert-butyl ester; 1-Boc-3-methyl 4-methylpiperazine-1,3-dicarboxylate; tert-Butyl 4-methyl-3-(methoxycarbonyl)piperazine-1-carboxylate; 4-Methyl-1,3-piperazinedicarboxylic acid 1-(1,1-dimethylethyl) ester; 851882-93-4; 1-N-Boc-4-methylpiperazine-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 4-Methyl-Piperazine-1,3-Dicarboxylic Acid 1-tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to traceability and consistency supports your regulatory and process development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.