Description

(2E)-3-(2-Bromophenyl)Acryloyl Chloride is a high-purity, reactive organic intermediate characterized by its acryloyl chloride functionality and brominated aromatic ring. This compound is a critical building block in advanced organic synthesis, enabling the efficient introduction of the (2-bromophenyl)acryloyl moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or acting as enzyme modulators.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Building block for monomers and polymers with specific optical or electronic properties.
• Chemical Research: Versatile reagent for academic and industrial R&D in organic chemistry, especially in cross-coupling reactions and heterocycle formation.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic systems.
• Peptide Mimetics: Employed in the design and synthesis of peptide analogs and isosteres for biochemical studies.

Basic Information

Product Name	(2E)-3-(2-Bromophenyl)Acryloyl Chloride
CAS No.	851664-10-3
Molecular Formula	C9H6BrClO
Molecular Weight	245.50 g/mol
Synonyms	(E)-3-(2-Bromophenyl)acryloyl chloride; 2-Bromocinnamoyl chloride; (2E)-3-(2-Bromophenyl)-2-propenoyl chloride; trans-3-(2-Bromophenyl)acryloyl chloride; 3-(2-Bromophenyl)-2-propenoyl chloride; (E)-3-(o-Bromophenyl)acryloyl chloride; 2-Bromo-trans-cinnamoyl chloride
EINECS	Contact for details

Quality Control

Our (2E)-3-(2-Bromophenyl)Acryloyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.