Description

tert-Butyl 3,6-Diazabicyclo[3.2.1]octane-3-carboxylate is a high-value, nitrogen-containing bicyclic building block used in advanced organic synthesis. This compound is a critical intermediate for medicinal chemistry research, enabling the construction of complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing new active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Ligand & Catalyst Development: Used to create sophisticated nitrogen-donor ligands for transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Agrochemical Research: Employed in the discovery and development of new crop protection agents and herbicides.
• Advanced Material Synthesis: A building block for functional polymers and materials requiring specific nitrogen-based functionalities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client projects.

Basic Information

Product Name	tert-Butyl 3,6-Diazabicyclo[3.2.1]octane-3-carboxylate
CAS No.	851526-81-3
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	3-(tert-Butoxycarbonyl)-3,6-diazabicyclo[3.2.1]octane; 3,6-Diazabicyclo[3.2.1]octane-3-carboxylic acid, 1,1-dimethylethyl ester; tert-Butyl 3,6-diazabicyclo[3.2.1]octane-3-carboxylate; 3-Boc-3,6-diazabicyclo[3.2.1]octane; BOC-3,6-Diazabicyclo[3.2.1]octane-3-carboxylate; 851526-81-3; 3,6-Diazabicyclo[3.2.1]octane-3-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3,6-Diazabicyclo[3.2.1]octane-3-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.