Description

1-Piperazinecarboxylic Acid, 3-(Hydroxymethyl)-4-(Phenylmethyl)-, 1,1-Dimethylethyl Ester is a sophisticated piperazine derivative and a key protected intermediate in advanced organic synthesis. This compound matters for its role as a crucial building block in the development of complex, high-value active pharmaceutical ingredients (APIs) and fine chemicals. Pharmaceutical R&D teams and fine chemical manufacturers need this high-purity intermediate to streamline the synthesis of novel therapeutic agents, particularly where precise stereochemistry and functional group protection are required.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Peptidomimetic Research: Used in the design and construction of peptidomimetics and constrained peptide analogs due to its piperazine core and protected functional groups.
• Chemical Biology Probes: Employed in the development of specialized molecular probes and tool compounds for studying biological pathways and target engagement.
• Agrochemical Synthesis: Acts as an intermediate in the research and development of novel agrochemicals with specific biological activity.
• Ligand and Catalyst Development: Utilized in the preparation of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Item	Detail
Product Name	1-Piperazinecarboxylic Acid, 3-(Hydroxymethyl)-4-(Phenylmethyl)-, 1,1-Dimethylethyl Ester
CAS No.	850834-14-9
Molecular Formula	C18H28N2O3
Molecular Weight	320.43 g/mol
Synonyms	tert-Butyl 3-(hydroxymethyl)-4-benzylpiperazine-1-carboxylate; 4-Benzyl-3-(hydroxymethyl)piperazine-1-carboxylic acid tert-butyl ester; Boc-4-benzyl-3-(hydroxymethyl)piperazine; N-Boc-3-(hydroxymethyl)-4-benzylpiperazine; 1-Boc-3-(hydroxymethyl)-4-benzylpiperazine; 3-(Hydroxymethyl)-4-benzyl-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 850834-14-9
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylic Acid, 3-(Hydroxymethyl)-4-(Phenylmethyl)-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.