Description

Alogliptin (Alogliptine, Alogliptina) is a potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor. This compound is a critical active pharmaceutical ingredient (API) used in the management of type 2 diabetes mellitus. It is essential for pharmaceutical manufacturers and research institutions developing innovative antidiabetic therapies. Our supply ensures high purity and consistent quality for reliable formulation and research outcomes.

Application

• Pharmaceutical API: Primary use as the active ingredient in oral antidiabetic medications for type 2 diabetes.
• Fixed-Dose Combination Drugs: Used in combination with other antidiabetic agents like metformin or pioglitazone.
• Pharmaceutical Research & Development: Serves as a key reference standard and building block in metabolic disease research.
• Formulation Development: Utilized in the development and testing of various dosage forms, including tablets.
• Analytical Standard: Acts as a high-purity standard for quality control and analytical method development (HPLC, LC-MS).
• Clinical Trial Material: Supplied as a GMP-grade material for pre-clinical and clinical studies.

Basic Information

Product Name	Alogliptin (Alogliptine, Alogliptina)
CAS No.	850649-61-5
Molecular Formula	C18H21N5O2
Molecular Weight	339.40 g/mol
Synonyms	Alogliptin; Alogliptine; Alogliptina; SYR-322; 2-({6-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile; Nesina (Brand Name); (R)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
EINECS	Contact for details

Quality Control

Our Alogliptin is manufactured and tested under strict quality systems. We provide material that meets or exceeds pharmaceutical-grade standards, with typical purity levels >98.5% (HPLC). Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ICH Q7 guidelines and can supply material suitable for GMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single unknown impurity ≤ 0.10%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.