Description

tert-Butyl 4-(3-Iodobenzyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine core with a halogenated benzyl substituent. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic compounds.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of protease inhibitors due to its protected piperazine structure.
• Ligand and Receptor Modulator Development: Employed in creating molecules that target G-protein coupled receptors (GPCRs) and other biological targets.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and protein function.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	tert-Butyl 4-(3-Iodobenzyl)Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	850375-09-6
Molecular Formula	C16H23IN2O2
Molecular Weight	402.27 g/mol
Synonyms	1-Boc-4-(3-iodobenzyl)piperazine; tert-Butyl 4-(3-iodobenzyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(3-iodobenzyl)piperazine; 4-(3-Iodobenzyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 850375-09-6; Boc-4-(3-iodobenzyl)piperazine; N-Boc-4-(3-iodobenzyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Iodobenzyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP (current Good Manufacturing Practice) compliance for use in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions or inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.