Description

tert-Butyl 4-(3-Formylbenzyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is a high-value, protected heterocyclic building block featuring both a formyl group and a Boc-protected piperazine moiety. This compound is critical for the synthesis of complex molecules, offering versatile sites for further functionalization and coupling reactions. It is primarily utilized by pharmaceutical and agrochemical R&D organizations for the development of novel active ingredients, particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for small molecule therapeutics.
• Medicinal Chemistry: Serves as a versatile scaffold for constructing libraries of compounds via reactions at the aldehyde and protected amine sites.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and pesticides.
• Chemical Biology: Employed in the synthesis of probes and ligands for studying biological targets and pathways.
• Peptidomimetics: The Boc-protected piperazine core is valuable for creating peptide-like structures with enhanced metabolic stability.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring high-purity advanced intermediates.

Basic Information

Product Name	tert-Butyl 4-(3-Formylbenzyl)Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	850375-08-5
Molecular Formula	C17H24N2O3
Molecular Weight	304.38 g/mol
Synonyms	1-Boc-4-(3-Formylbenzyl)piperazine; tert-Butyl 4-[(3-formylphenyl)methyl]piperazine-1-carboxylate; 4-(3-Formylbenzyl)-1-(tert-butoxycarbonyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(3-formylbenzyl)piperazine; 850375-08-5; 4-[(3-Formylphenyl)methyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; Boc-4-(3-formylbenzyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Formylbenzyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.