Description

1-Piperazineacetonitrile, 4-Methyl--α--Methylene- is a specialized organic compound belonging to the piperazine family, serving as a versatile and high-value building block in advanced chemical synthesis. Its unique structure, featuring both a nitrile and a methylene group on a methylated piperazine core, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, anti-infectives, and other bioactive molecules.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and plant growth regulators, leveraging its piperazine scaffold.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Acts as a building block for creating complex dyes, pigments, and other performance chemicals.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	1-Piperazineacetonitrile, 4-Methyl--α--Methylene-
CAS No.	850200-56-5
Molecular Formula	C8H13N3
Molecular Weight	151.21 g/mol
Synonyms	4-Methyl-α-methylenepiperazine-1-acetonitrile; 1-(Cyanomethyl)-4-methyl-1,2,3,6-tetrahydropyridine; 4-Methyl-1,2,3,6-tetrahydropyridine-1-acetonitrile; 1-Piperazineacetonitrile, 4-methyl-α-methylene-; 4-Methyl-δ1-piperazineacetonitrile; (4-Methyl-1,2,3,6-tetrahydropyridin-1-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our production of 1-Piperazineacetonitrile, 4-Methyl--α--Methylene- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support cGMP-compliant manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.