Description

Ethyl 1-Benzyl-3-Hydroxypiperidine-4-Carboxylate is a versatile piperidine derivative, a crucial building block in modern organic synthesis. This compound matters for its role as a key chiral intermediate in the development of complex, biologically active molecules. Pharmaceutical R&D and fine chemical manufacturers need it for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used in the construction of complex piperidine-based scaffolds for high-throughput screening and lead optimization.
• Asymmetric Synthesis: Serves as a valuable starting material or intermediate in stereoselective synthesis due to its defined stereochemistry.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for agrochemical and material science applications.
• Academic & Industrial Research: Utilized in chemical research for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	Ethyl 1-Benzyl-3-Hydroxypiperidine-4-Carboxylate
CAS No.	850040-08-3
Molecular Formula	C15H21NO3
Molecular Weight	263.33 g/mol
Synonyms	Ethyl 1-benzyl-3-hydroxypiperidine-4-carboxylate; 4-Piperidinecarboxylic acid, 3-hydroxy-1-(phenylmethyl)-, ethyl ester; 1-Benzyl-3-hydroxypiperidine-4-carboxylic acid ethyl ester; Ethyl 1-benzyl-3-hydroxy-4-piperidinecarboxylate; 850040-08-3; 1-Benzyl-3-hydroxypiperidine-4-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-Benzyl-3-Hydroxypiperidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.