Description

Acetic Acid, 2,2,2-Trifluoro-, (2Z)-2-(2-Piperazinylidene)Hydrazide CAS NO 849832-73-1 is a specialized fluorinated organic compound featuring a unique piperazine-hydrazide hybrid structure. This molecule is of significant interest for its potential as a high-value building block in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis. The compound's structure offers a versatile scaffold for creating novel active ingredients with tailored properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Serves as a building block for developing new-generation herbicides, fungicides, or insecticides where the trifluoroacetyl and hydrazide groups contribute to biological activity.
• Ligand Synthesis in Catalysis: Used to create complex chelating ligands for transition metal catalysts, useful in asymmetric synthesis and cross-coupling reactions.
• Material Science Precursor: Potential monomer or modifier in the synthesis of specialized polymers, such as polyamides or polyhydrazides, with unique thermal or chemical resistance properties.
• Bioconjugation Chemistry: The reactive hydrazide group can be utilized for site-specific labeling and conjugation of biomolecules like proteins or antibodies in diagnostic assay development.

Basic Information

Product Name	Acetic Acid, 2,2,2-Trifluoro-, (2Z)-2-(2-Piperazinylidene)Hydrazide
CAS No.	849832-73-1
Molecular Formula	C8H11F3N4O
Molecular Weight	236.20 g/mol
Synonyms	2,2,2-Trifluoroacetic Acid (2Z)-2-(2-Piperazinylidene)Hydrazide; (2Z)-2-(Piperazin-2-ylidene)hydrazide of 2,2,2-Trifluoroacetic Acid; Trifluoroacethydrazide, N'-(piperazin-2-ylidene)-; 849832-73-1; 2,2,2-Trifluoro-N'-(piperazin-2-ylidene)acetohydrazide; N'-(Piperazin-2-ylidene)-2,2,2-trifluoroacetohydrazide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. For this advanced intermediate, quality is assured through multiple analytical techniques including HPLC for purity, NMR for structural confirmation, and LC-MS for identity and impurity profiling. We adhere to a cGMP-aligned quality management system for consistent batch-to-batch reproducibility.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to moisture and strong bases; ensure the container is kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.