Description

4-Cyclohexylpiperazine-1-Carboximidamide Hydroiodide is a high-purity, pharmaceutically relevant intermediate characterized by its unique amidine functionality. This compound is of significant value in medicinal chemistry for the synthesis of novel therapeutic agents, particularly as a key building block for protease inhibitors and other bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in drug discovery and process development for targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting enzymatic pathways.
• Protease Inhibitor Development: Used in research for creating potential inhibitors for proteases involved in viral replication and other disease mechanisms.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Utilized in the development of chemical probes to study biological processes and protein function.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	4-Cyclohexylpiperazine-1-Carboximidamide Hydroiodide
CAS No.	849776-37-0
Molecular Formula	C11H23IN4
Molecular Weight	338.23 g/mol
Synonyms	4-Cyclohexylpiperazine-1-carboximidamide hydroiodide; 1-Piperazinecarboximidamide, 4-cyclohexyl-, monohydroiodide; 4-Cyclohexyl-1-piperazinecarboximidamide hydroiodide; N-Cyclohexylpiperazine-1-carboxamidine hydroiodide; 849776-37-0; 4-Cyclohexylpiperazinecarboximidamide HI; Cyclohexylpiperazine amidine hydroiodide
EINECS	Contact for details

Quality Control

Our 4-Cyclohexylpiperazine-1-Carboximidamide Hydroiodide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to support both non-GMP and cGMP supply chains, ensuring reliable and traceable material for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.