Description

4-Pyridin-2-Ylpiperazine-1-Carboximidamide Hydroiodide is a high-purity, advanced pharmaceutical intermediate of significant interest in modern medicinal chemistry. This compound matters for its role as a key building block in the synthesis of novel bioactive molecules, particularly those targeting central nervous system and oncological pathways. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand Synthesis: Used in the development of selective ligands for various receptor subtypes, aiding in pharmacological profiling.
• Chemical Biology Probes: Employed in the creation of tool compounds for studying biological pathways and target validation.
• Fine Chemical Production: Integral to multi-step synthetic routes for producing high-value, complex organic molecules.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services.

Basic Information

Product Name	4-Pyridin-2-Ylpiperazine-1-Carboximidamide Hydroiodide
CAS No.	849776-32-5
Molecular Formula	C10H16IN5
Molecular Weight	333.18 g/mol
Synonyms	2-(4-Carbamimidoylpiperazin-1-yl)pyridine hydroiodide; 1-Piperazinecarboximidamide, 4-(2-pyridinyl)-, monohydroiodide; 4-(Pyridin-2-yl)piperazine-1-carboximidamide hydroiodide; 4-(2-Pyridyl)piperazine-1-carboxamidine hydroiodide; 2-(4-Carbamimidoylpiperazin-1-yl)pyridine; 4-(2-Pyridinyl)-1-piperazinecarboximidamide hydroiodide
EINECS	Contact for details

Quality Control

Our 4-Pyridin-2-Ylpiperazine-1-Carboximidamide Hydroiodide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ICH guidelines ensure the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.