Description

2-Bromo-6-Morpholinopyrazine is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a versatile intermediate, enabling the construction of complex molecular architectures through selective cross-coupling and substitution reactions. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, particularly in the development of kinase inhibitors and other bioactive small molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies.
• Kinase Inhibitor Development: Used in medicinal chemistry for constructing core scaffolds of protein kinase inhibitors.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides and fungicides.
• Material Science: Employed in the synthesis of organic electronic materials and ligands for catalysis.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target engagement.

Basic Information

Product Name	2-Bromo-6-Morpholinopyrazine
CAS No.	848841-62-3
Molecular Formula	C8H10BrN3O
Molecular Weight	244.09 g/mol
Synonyms	2-Bromo-6-morpholinopyrazine; 6-Bromo-2-morpholinopyrazine; Pyrazine, 2-bromo-6-morpholino-; 2-Morpholino-6-bromopyrazine; 848841-62-3; AKOS025310999; BRN 15484605; CS-W009767
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Morpholinopyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.