Description

Cyclohexaneacetic Acid, α-[(2-Pyrazinylcarbonyl)Amino]-, Methyl Ester, (αs)- is a high-purity, chiral synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound matters for its role as a key building block in the synthesis of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel therapeutic candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Fine Chemical Production: Serves as a specialized building block for synthesizing complex fragrance compounds, flavors, and other high-value specialty chemicals.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies in asymmetric synthesis and catalysis.
• Peptidomimetic Research: Useful in the design and synthesis of peptide analogs and mimetics due to its structural features.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in enantioselective transformations.

Basic Information

Product Name	Cyclohexaneacetic Acid, α-[(2-Pyrazinylcarbonyl)Amino]-, Methyl Ester, (αs)-
CAS No.	848777-29-7
Molecular Formula	C15H19N3O3
Molecular Weight	289.33 g/mol
Synonyms	(αS)-α-[[(2-Pyrazinylcarbonyl)amino]methyl]cyclohexaneacetic acid methyl ester; Methyl (αS)-α-[[(pyrazine-2-carbonyl)amino]methyl]cyclohexaneacetate; (S)-Methyl 2-((2-picolinamido)methyl)cyclohexaneacetate (related structure); Chiral pyrazine carboxamide derivative; Cyclohexaneacetic acid, α-[(2-pyrazinylcarbonyl)amino]-, methyl ester, (αS)-; AS-848777-29-7; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our Cyclohexaneacetic Acid, α-[(2-Pyrazinylcarbonyl)Amino]-, Methyl Ester, (αs)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.