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2-(14,15-Epoxyeicosatrienoyl) Glycerol CAS NO 848667-56-1


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CAS No.:848667-56-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(14,15-Epoxyeicosatrienoyl) Glycerol is a specialized eicosanoid-derived lipid signaling molecule, specifically an epoxy fatty acid ester of glycerol. This compound is of significant interest in biochemical and pharmacological research due to its role as a bioactive metabolite of arachidonic acid, influencing critical cellular processes. It is primarily utilized by research institutions and pharmaceutical developers focused on cardiovascular, renal, and inflammatory pathways. The product is supplied to meet the stringent purity requirements of advanced life science research.

Application

  • Biochemical Research: Used as a reference standard and experimental tool in studies of cytochrome P450 (CYP) epoxygenase pathways and eicosanoid biology.
  • Pharmacological Studies: Investigated for its potential vasodilatory, anti-inflammatory, and organ-protective effects in preclinical models.
  • Cell Signaling Pathway Analysis: Employed to study the activation and modulation of specific receptors and intracellular signaling cascades related to epoxy fatty acids.
  • Metabolite Identification: Serves as a critical analytical standard in mass spectrometry and chromatography for identifying and quantifying related metabolites in biological samples.
  • Drug Discovery & Development: A key intermediate or target molecule in programs aiming to develop novel therapeutics for hypertension, pain, and metabolic disorders.

Basic Information

Product Name 2-(14,15-Epoxyeicosatrienoyl) Glycerol
CAS No. 848667-56-1
Molecular Formula C23H38O5
Molecular Weight 394.55 g/mol
Synonyms 14(15)-EpETrE-G; 14,15-Epoxyeicosatrienoic Acid Glycerol Ester; 2-Glyceryl 14,15-Epoxyeicosatrienoate; 2-(14,15-EET)-Glycerol; 14,15-EET-G; 2-(14,15-Epoxy-5Z,8Z,11Z-eicosatrienoyl)-glycerol; 2-Monoacylglycerol of 14,15-EET; Glycerol 2-(14,15-epoxyeicosatrienoyl) ether (incorrect but common alias)
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Quality Control

Every batch of 2-(14,15-Epoxyeicosatrienoyl) Glycerol is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results from HPLC, NMR, and mass spectrometry are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and bases.

Specification

Item Specification
Appearance Colorless to pale yellow viscous oil or solid
Identification (HPLC/MS) Conforms to reference standard
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 95%
Related Substances (HPLC) Total impurities ≤ 5.0%
Solvent Residue (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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