Description

(S)-4-n-Boc-Piperazine-2-Carboxylic Acid CAS NO 848482-93-9 is a high-purity, chiral piperazine derivative, a critical building block in modern pharmaceutical synthesis. Its primary value lies in its role as a key intermediate for constructing complex molecules with specific stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This compound is particularly sought after by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, especially in therapeutic areas requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in oncology, neurology, and antiviral research.
• Peptidomimetic Chemistry: Used to incorporate constrained, stereodefined piperazine motifs into peptide backbones to enhance stability and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and receptor interactions.
• Custom Synthesis & Contract Manufacturing: A standard request for custom synthesis houses supporting pharmaceutical R&D and scale-up activities.
• Academic Research: Used in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(S)-4-n-Boc-Piperazine-2-Carboxylic Acid
CAS No.	848482-93-9
Molecular Formula	C10H18N2O4
Molecular Weight	230.26 g/mol
Synonyms	(S)-1-Boc-piperazine-2-carboxylic acid; (S)-4-(tert-Butoxycarbonyl)piperazine-2-carboxylic acid; (S)-1-tert-Butyl 2-carboxypiperazine-1,2-dicarboxylate; (2S)-4-[(2-Methylpropan-2-yl)oxycarbonyl]piperazine-2-carboxylic acid; (S)-N-Boc-piperazine-2-carboxylic acid; (S)-Boc-piperazine-2-COOH; (S)-4-Boc-piperazine-2-carboxylic acid; (S)-1-N-Boc-2-piperazinecarboxylic acid
EINECS	Contact for details

Quality Control

Our (S)-4-n-Boc-Piperazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and pre-clinical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.