Description

(R)-2-(Hydroxymethyl)-1-Methylpiperazine is a chiral piperazine derivative of significant importance in modern synthetic chemistry. This compound serves as a versatile and high-value chiral building block for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for metal-catalyzed asymmetric synthesis, enabling high stereoselectivity in critical bond-forming reactions.
• Agrochemical Synthesis: Employed in the research and development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Fine Chemical Building Block: Integral for constructing complex molecular architectures in custom synthesis and process development for high-value specialty chemicals.
• Bioconjugation and Linker Chemistry: The hydroxymethyl group provides a handle for further functionalization, useful in bioconjugation and linker strategies for prodrugs or diagnostic agents.

Basic Information

Product Name	(R)-2-(Hydroxymethyl)-1-Methylpiperazine
CAS No.	848482-33-7
Molecular Formula	C7H16N2O
Molecular Weight	144.22 g/mol
Synonyms	(R)-1-Methyl-2-(hydroxymethyl)piperazine; (R)-1-Methylpiperazine-2-methanol; (2R)-2-(Hydroxymethyl)-1-methylpiperazine; (R)-HMP; (R)-2-Hydroxymethyl-1-methylpiperazine; (R)-N-Methyl-2-piperazinemethanol; (R)-1-Methyl-2-piperazinemethanol
EINECS	Contact for details

Quality Control

Our (R)-2-(Hydroxymethyl)-1-Methylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.