Description

Ethanone, 1-[4-[(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Sulfonyl]-1-Piperazinyl]-2-Phenoxy- is a high-purity, advanced pharmaceutical intermediate characterized by its complex molecular architecture featuring a phenoxy, piperazinyl, and benzodioxinyl sulfonyl groups. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapeutic research. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation drug candidates.

Application

• Pharmaceutical Intermediate: Critical building block in the research and development of new chemical entities (NCEs) for potential therapeutic applications.
• CNS Drug Discovery: Used in the synthesis of compounds targeting neurological receptors, owing to its specific structural motifs.
• Kinase Inhibitor Research: Serves as a precursor in the development of kinase inhibitor libraries for oncology and anti-inflammatory drug discovery.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale synthesis for clinical trial material production.
• Biochemical Research: Utilized as a reference standard or a probe molecule in pharmacological and biochemical assays.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) performing bespoke synthesis for client-specific molecular targets.

Basic Information

Product Name	Ethanone, 1-[4-[(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Sulfonyl]-1-Piperazinyl]-2-Phenoxy-
CAS No.	847840-70-4
Molecular Formula	C20H22N2O5S
Molecular Weight	402.46 g/mol
Synonyms	1-[4-[(2,3-Dihydro-1,4-benzodioxin-6-yl)sulfonyl]-1-piperazinyl]-2-phenoxyethanone; 2-Phenoxy-1-[4-[(2,3-dihydro-1,4-benzodioxin-6-yl)sulfonyl]piperazin-1-yl]ethanone; 847840-70-4; UNII-9H0F6W3V6I; 9H0F6W3V6I; Phenoxy-1-(4-(2,3-dihydrobenzo[b][1,4]dioxine-6-sulfonyl)piperazin-1-yl)ethanone; AKOS025310999; A-973
EINECS	Contact for details

Quality Control

Our Ethanone, 1-[4-[(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Sulfonyl]-1-Piperazinyl]-2-Phenoxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.