Description

(S)-4-Boc-2-((S)-Hydroxy(Phenyl)Methyl)Morpholine CAS NO 847805-32-7 is a high-purity, non-racemic chiral building block and intermediate of significant synthetic utility. This compound is valued for its role in the stereoselective construction of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates, particularly for central nervous system (CNS) and antiviral targets.
• Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis (e.g., hydrogenation, cross-coupling).
• Peptidomimetic Scaffold: Used in medicinal chemistry to create morpholine-based peptidomimetics and protease inhibitors.
• Agrochemical Synthesis: Employed in the research and development of chiral agrochemicals requiring specific stereochemistry for enhanced activity.
• Academic Research: A valuable tool for methodological studies in organic synthesis, focusing on stereocontrol and new reaction development.
• Custom Synthesis: Provides a defined chiral center for contract research organizations (CROs) and CDMOs engaged in custom chemical synthesis projects.

Basic Information

Product Name	(S)-4-Boc-2-((S)-Hydroxy(Phenyl)Methyl)Morpholine
CAS No.	847805-32-7
Molecular Formula	C16H23NO4
Molecular Weight	293.36 g/mol
Synonyms	(2S,2'S)-4-(tert-Butoxycarbonyl)-2-(hydroxy(phenyl)methyl)morpholine; (S)-4-Boc-2-((S)-Hydroxybenzyl)Morpholine; tert-Butyl (2S,2'S)-2-(hydroxy(phenyl)methyl)morpholine-4-carboxylate; (2S,2'S)-N-Boc-2-(hydroxy(phenyl)methyl)morpholine; (S,S)-4-Boc-2-(Hydroxy(Phenyl)Methyl)Morpholine; Morpholine, 4-[(1,1-dimethylethoxy)carbonyl]-2-[(1S)-hydroxy(phenyl)methyl]-, (2S)-; BOC-(S)-HMorpholine
EINECS	Contact for details

Quality Control

Our (S)-4-Boc-2-((S)-Hydroxy(Phenyl)Methyl)Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles are available upon request. We support compliance with cGMP, ICH guidelines, and REACH regulations for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.