Description

(S)-6-Hydroxymethyl-Morpholin-3-One is a high-value chiral building block and pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering a defined stereocenter and functional handles for further chemical elaboration. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials requiring high enantiomeric purity.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	(S)-6-Hydroxymethyl-Morpholin-3-One
CAS No.	847805-30-5
Molecular Formula	C5H9NO3
Molecular Weight	131.13 g/mol
Synonyms	(3S)-6-(Hydroxymethyl)-3-morpholinone; (S)-6-(Hydroxymethyl)morpholin-3-one; (S)-3-Morpholinone, 6-(hydroxymethyl)-; (S)-6-Hydroxymethyl-3-morpholinone; (S)-6-Hydroxymethylmorpholin-3-one; Morpholin-3-one, 6-(hydroxymethyl)-, (3S)-; (S)-Enantiomer of 6-Hydroxymethylmorpholin-3-one
EINECS	Contact for details

Quality Control

We supply (S)-6-Hydroxymethyl-Morpholin-3-One in high-purity grades suitable for research and cGMP manufacturing. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.