Description

1-[(2,4-Difluorophenyl)Sulfonyl]Piperazine is a specialized sulfonamide derivative featuring a piperazine core, a key structural motif in medicinal chemistry. This compound serves as a versatile and high-purity pharmaceutical intermediate for the research and development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the bioactivity of the difluorophenylsulfonyl moiety.
• Chemical Biology Probe Synthesis: Employed to create tool compounds for studying enzyme function and biological pathways in academic and industrial research settings.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific molecules under cGMP or research-grade conditions.
• Library Synthesis for High-Throughput Screening: Serves as a core scaffold for generating diverse compound libraries to identify new hits in drug discovery campaigns.

Basic Information

Product Name	1-[(2,4-Difluorophenyl)Sulfonyl]Piperazine
CAS No.	847783-38-4
Molecular Formula	C10H12F2N2O2S
Molecular Weight	262.28 g/mol
Synonyms	1-(2,4-Difluorophenylsulfonyl)piperazine; 2,4-Difluoro-N-(piperazin-1-yl)benzenesulfonamide; Piperazine, 1-[(2,4-difluorophenyl)sulfonyl]-; N-(2,4-Difluorophenylsulfonyl)piperazine; 847783-38-4; 1-(2,4-Difluorobenzenesulfonyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-[(2,4-Difluorophenyl)Sulfonyl]Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.