Description

tert-Butyl 4-tritylpiperazine-1-carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex piperazine-based pharmacophores.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, leveraging the trityl and Boc protecting groups for selective functionalization.
• Peptidomimetic Synthesis: Serves as a constrained scaffold in the design and synthesis of peptide mimics for therapeutic applications.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis or as a precursor for functionalized materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and target engagement.
• Agrochemical Research: Intermediate in the development of new crop protection agents and pesticides.

Basic Information

Item	Details
Product Name	tert-Butyl 4-tritylpiperazine-1-carboxylate
CAS No.	847556-47-2
Molecular Formula	C30H36N2O2
Molecular Weight	456.62 g/mol
Synonyms	1-Boc-4-tritylpiperazine; tert-Butyl 4-(triphenylmethyl)-1-piperazinecarboxylate; 4-(Triphenylmethyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-(triphenylmethyl)-1-piperazinecarboxylate; Boc-4-tritylpiperazine; N-Boc-4-tritylpiperazine; 1-N-Boc-4-N-tritylpiperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-tritylpiperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.