Description

4-Amino-3-Methyl-1-Piperidinecarboxylic Acid Benzyl Ester is a specialized piperidine derivative that serves as a crucial chiral building block and intermediate in advanced organic synthesis. Its value lies in its functionalized structure, which provides a versatile scaffold for constructing complex molecules with high stereochemical control. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), novel drug candidates, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Asymmetric Catalysis: Employed as a precursor or ligand in catalytic systems for stereoselective chemical transformations.
• Peptidomimetics Research: Serves as a constrained amino acid analog in the design of peptide-like molecules with enhanced metabolic stability.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Amino-3-Methyl-1-Piperidinecarboxylic Acid Benzyl Ester
CAS No.	847458-97-3
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	Benzyl 4-Amino-3-methylpiperidine-1-carboxylate; 1-Carbobenzyloxy-4-amino-3-methylpiperidine; 4-Amino-3-methyl-1-piperidinecarboxylic acid phenylmethyl ester; 3-Methyl-4-aminopiperidine-1-carboxylic acid benzyl ester; Cbz-4-Amino-3-methylpiperidine; 1-N-Cbz-4-Amino-3-methylpiperidine; (3-Methyl-4-aminopiperidin-1-yl)(phenyl)methanone (alternative representation); 847458-97-3
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Methyl-1-Piperidinecarboxylic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.