Description

n-[3-Cyano-1-(3-Isopropoxypropyl)-5-Oxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidin-2-Ylidene]-2-Ethoxybenzamide CAS NO 847268-73-9 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in the research and development of novel therapeutic agents, particularly in the field of oncology and targeted drug discovery. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel, high-potency active pharmaceutical ingredients (APIs).
• Oncology Research: Serves as a core structural component in the development of investigational anti-cancer drugs and kinase inhibitors.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization processes for new drug candidates.
• Preclinical Development: Supplied for the production of batches used in pharmacological and toxicological studies.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of specialized, non-commercial compounds for client research.
• Chemical Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API production.

Basic Information

Product Name	n-[3-Cyano-1-(3-Isopropoxypropyl)-5-Oxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidin-2-Ylidene]-2-Ethoxybenzamide
CAS No.	847268-73-9
Molecular Formula	C27H27N5O4
Molecular Weight	485.54 g/mol
Synonyms	2-Ethoxy-N-[3-cyano-1-(3-isopropoxypropyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidin-2-ylidene]benzamide; UNII-6Q9F4J0K8I; 6Q9F4J0K8I; BDBM50157857; AKOS025310991; ZINC000006714757; A1-02297; CHEMBL3186662
EINECS	Contact for details

Quality Control

Our n-[3-Cyano-1-(3-Isopropoxypropyl)-5-Oxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidin-2-Ylidene]-2-Ethoxybenzamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.