Description

4-Hydroxy-Piperidine-1,2-Dicarboxylic Acid 1-Benzyl Ester 2-Methyl Ester is a high-purity, functionalized piperidine derivative that serves as a critical chiral building block and advanced pharmaceutical intermediate. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules with specific stereochemistry and biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides requiring specific stereochemical configurations for efficacy.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Catalyst & Ligand Precursor: Can be utilized to develop novel chiral catalysts and ligands for asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	4-Hydroxy-Piperidine-1,2-Dicarboxylic Acid 1-Benzyl Ester 2-Methyl Ester
CAS No.	847029-99-6
Molecular Formula	C16H21NO5
Molecular Weight	307.34 g/mol
Synonyms	1-Benzyl 2-methyl 4-hydroxypiperidine-1,2-dicarboxylate; 4-Hydroxypiperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester; Methyl 1-benzyl 4-hydroxy-1,2-piperidinedicarboxylate; 1,2-Piperidinedicarboxylic acid, 4-hydroxy-, 1-benzyl 2-methyl ester; 847029-99-6; (4-Hydroxypiperidine-1,2-diyl)dicarboxylic acid 1-benzyl ester 2-methyl ester
EINECS	Contact for details

Quality Control

Our production of 4-Hydroxy-Piperidine-1,2-Dicarboxylic Acid 1-Benzyl Ester 2-Methyl Ester adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.