Description

1-Cbz-2,2-Dimethyl-Piperazine is a high-purity, protected piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Peptidomimetic Chemistry: Used to introduce the 2,2-dimethyl-piperazine moiety into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and medicinal chemistry applications.
• Chemical Research & Development: Serves as a versatile scaffold for constructing novel chemical libraries in drug discovery programs.
• Custom Synthesis: A starting material for the contract manufacturing of high-value, proprietary compounds for the life sciences industry.

Basic Information

Product Name	1-Cbz-2,2-Dimethyl-Piperazine
CAS No.	846052-89-9
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-2,2-dimethylpiperazine; 2,2-Dimethyl-1-(phenylmethoxy)carbonylpiperazine; 1-Carbobenzoxy-2,2-dimethylpiperazine; N-Cbz-2,2-dimethylpiperazine; 1-(Benzyloxycarbonyl)-2,2-dimethylpiperazine; 2,2-Dimethylpiperazine-1-carboxylic acid benzyl ester; Z-2,2-Dimethylpiperazine
EINECS	Contact for details

Quality Control

Our 1-Cbz-2,2-Dimethyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.