Description

4-(7-Hydroxy-Naphthalen-1-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a naphthalene-piperazine hybrid structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry research.
• API Synthesis: Serves as a crucial building block for constructing complex molecules with potential biological activity in central nervous system (CNS) and oncology drug discovery.
• Chemical Research: Used in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring a functionalized naphthalene-piperazine scaffold.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4-(7-Hydroxy-Naphthalen-1-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	846033-00-9
Molecular Formula	C19H24N2O3
Molecular Weight	328.41 g/mol
Synonyms	1-Boc-4-(7-hydroxynaphthalen-1-yl)piperazine; tert-Butyl 4-(7-hydroxynaphthalen-1-yl)piperazine-1-carboxylate; 4-(7-Hydroxy-1-naphthyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-(7-hydroxy-1-naphthalenyl)-1-piperazinecarboxylate; N-Boc-4-(7-hydroxynaphthalen-1-yl)piperazine; Piperazine-1-carboxylic acid tert-butyl ester 4-(7-hydroxy-naphthalen-1-yl) derivative
EINECS	Contact for details

Quality Control

Our 4-(7-Hydroxy-Naphthalen-1-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.