Description

4-Methoxy-3-(3-(4-Methylpiperazin-1-Yl)Propoxy)Aniline is a high-purity, advanced pharmaceutical intermediate characterized by its specific aniline and piperazine-based structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its unique functional groups serve as key building blocks. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the manufacture of complex drug molecules and active pharmaceutical ingredients (APIs).
• Oncology Drug Research: Used in the research and development of targeted cancer therapies and kinase inhibitors.
• CNS Drug Development: Serves as a building block for compounds targeting neurological and psychiatric disorders.
• Chemical Synthesis & Process R&D: Employed in route scouting, optimization, and scale-up activities in process chemistry.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for GMP and non-GMP production campaigns.
• Academic & Industrial Research: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Methoxy-3-(3-(4-Methylpiperazin-1-Yl)Propoxy)Aniline
CAS No.	846023-55-0
Molecular Formula	C15H25N3O2
Molecular Weight	279.38 g/mol
Synonyms	4-Methoxy-3-[3-(4-methyl-1-piperazinyl)propoxy]aniline; 3-(3-(4-Methylpiperazin-1-yl)propoxy)-4-methoxyaniline; 1-[3-[(4-Amino-2-methoxyphenoxy)propyl]-4-methylpiperazine; Benzenamine, 4-methoxy-3-[3-(4-methyl-1-piperazinyl)propoxy]-; 846023-55-0
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-(3-(4-Methylpiperazin-1-Yl)Propoxy)Aniline is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.