Description

3-Oxo-4-Phenyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity pharmaceutical intermediate of significant importance in modern organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex piperazine-based scaffolds. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• API Development: Used in research and development for constructing the core piperazine moiety in potential new active pharmaceutical ingredients.
• Chemical Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Custom Synthesis: Serves as a starting material for contract manufacturing and the production of specialized, non-commercial compounds for research.
• Process Chemistry: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	3-Oxo-4-Phenyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	845973-49-1
Molecular Formula	C15H20N2O3
Molecular Weight	276.33 g/mol
Synonyms	tert-Butyl 3-oxo-4-phenylpiperazine-1-carboxylate; 1-Boc-3-oxo-4-phenylpiperazine; 4-Phenyl-3-oxopiperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-phenyl-2,3-dioxopiperazine; 3-Keto-4-phenylpiperazine-1-carboxylic acid tert-butyl ester; N-Boc-3-oxo-4-phenylpiperazine; 845973-49-1
EINECS	Contact for details

Quality Control

Our 3-Oxo-4-Phenyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability, consistency, and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.