Description

4-[4-[2-(Cyclopropylmethoxy)-5-Methylsulfonylbenzoyl]Piperazin-1-Yl]-3-Fluorobenzonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of targeted therapeutic agents, offering researchers and manufacturers a reliable building block for complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers engaged in the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Kinase Inhibitor Research: Used in the research and development of potent and selective kinase inhibitors due to its specific molecular scaffold.
• Chemical Biology Probes: Employed in the design of chemical probes for studying specific biological pathways and target validation.
• Custom Synthesis: A vital starting material for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis for client projects.
• Process Chemistry Development: Used by process chemists to develop and scale up efficient synthetic routes for complex target molecules.

Basic Information

Product Name	4-[4-[2-(Cyclopropylmethoxy)-5-Methylsulfonylbenzoyl]Piperazin-1-Yl]-3-Fluorobenzonitrile
CAS No.	845609-54-3
Molecular Formula	C23H24FN3O4S
Molecular Weight	457.52 g/mol
Synonyms	3-Fluoro-4-[4-[[2-(cyclopropylmethoxy)-5-(methylsulfonyl)benzoyl]piperazin-1-yl]benzonitrile; 4-[4-[2-(Cyclopropylmethoxy)-5-(methylsulfonyl)benzoyl]-1-piperazinyl]-3-fluorobenzonitrile; UNII-9K6P3H8Q8F; 9K6P3H8Q8F; Benzonitrile, 3-fluoro-4-[4-[[2-(cyclopropylmethoxy)-5-(methylsulfonyl)benzoyl]-1-piperazinyl]-; 845609-54-3; 4-(4-(2-(Cyclopropylmethoxy)-5-(methylsulfonyl)benzoyl)piperazin-1-yl)-3-fluorobenzonitrile
EINECS	Contact for details

Quality Control

Our production of 4-[4-[2-(Cyclopropylmethoxy)-5-Methylsulfonylbenzoyl]Piperazin-1-Yl]-3-Fluorobenzonitrile adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.