Description

tert-Butyl 4-(4-Formylbenzyl)Piperazine-1-Carboxylate is a high-value, protected piperazine derivative featuring a reactive benzaldehyde moiety, making it a versatile and critical building block in advanced organic synthesis. Its primary value lies in its dual functionality, serving as a key precursor for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Scaffold: Used to create diverse compound libraries via reactions at the formyl group (e.g., reductive amination, condensation) and manipulation of the Boc-protected piperazine nitrogen.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel ligands for metal catalysis or as a component in organocatalysts.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides that incorporate piperazine and aromatic aldehyde pharmacophores.
• Polymer Modification: Can be used to introduce functional groups into polymer chains for creating specialty materials with tailored properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological targets and pathways due to its derivatizable handles.

Basic Information

Product Name	tert-Butyl 4-(4-Formylbenzyl)Piperazine-1-Carboxylate
CAS No.	844891-09-4
Molecular Formula	C17H24N2O3
Molecular Weight	304.39 g/mol
Synonyms	1-Boc-4-(4-Formylbenzyl)piperazine; tert-Butyl 4-[(4-formylphenyl)methyl]piperazine-1-carboxylate; 4-Formylbenzylpiperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(4-formylbenzyl)piperazine; N-Boc-4-(4-formylbenzyl)piperazine; 844891-09-4; BOC-4-(4-Formylbenzyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Formylbenzyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards expected for non-GMP pharmaceutical intermediates, ensuring reliable performance in your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.