Description

1-(2-Fluoro-4-Nitrophenyl)-3-Methylpiperazine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fluorinated and nitrated aromatic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular modifications. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its fluorinated aromatic system for enhanced biological activity.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, including coupling reactions and piperazine ring modifications.
• Life Science Research: Employed in biochemical and pharmacological studies as a reference standard or a tool compound for target validation.
• Material Science: Investigated for potential use in the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	1-(2-Fluoro-4-Nitrophenyl)-3-Methylpiperazine
CAS No.	837421-28-0
Molecular Formula	C11H14FN3O2
Molecular Weight	239.25 g/mol
Synonyms	3-Methyl-1-(2-fluoro-4-nitrophenyl)piperazine; 1-(2-Fluoro-4-nitrophenyl)-3-methylpiperazine; 2-Fluoro-4-nitro-N-(3-methylpiperazin-1-yl)aniline; 837421-28-0; 1-(2-Fluoro-4-nitrophenyl)-3-methyl-piperazine
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-4-Nitrophenyl)-3-Methylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent oxidation and moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.