Description

Indeglitazar CAS NO 835619-41-5 is a synthetic, high-purity pharmaceutical compound belonging to the class of dual peroxisome proliferator-activated receptor (PPAR) α/γ agonists. This compound is of significant interest for advanced research and development within the pharmaceutical industry due to its targeted mechanism of action. It is primarily utilized by pharmaceutical companies, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in metabolic disorder research and novel drug development.

Application

• Pharmaceutical R&D: Serves as a key active pharmaceutical ingredient (API) intermediate or reference standard in the development of novel therapeutics for metabolic syndromes.
• Metabolic Disorder Research: Used as a potent research tool in preclinical and clinical studies targeting type 2 diabetes, dyslipidemia, and insulin resistance.
• Mechanistic Studies: Employed in biochemical and pharmacological assays to investigate PPAR receptor activation pathways and related biological effects.
• Analytical Standard: Functions as a high-purity certified reference material (CRM) for method development, validation, and quality control testing in analytical laboratories.
• Process Chemistry: Utilized in the scale-up and optimization of synthetic routes for the production of related pharmaceutical compounds.

Basic Information

Product Name	Indeglitazar
CAS No.	835619-41-5
Molecular Formula	C22H21NO5S
Molecular Weight	411.47 g/mol
Synonyms	Indeglitazar; 2-[[4-[(3,5-Dimethyl-4-isoxazolyl)methoxy]-2-methylphenyl]methylsulfanyl]-1H-benzimidazole-5-carboxylic acid; PPM-204; GSK-677954; PPAR α/γ dual agonist; UNII-6J8K6QH8QK
EINECS	Contact for details

Quality Control

Our Indeglitazar is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under appropriate conditions to prevent degradation. For long-term storage, consider desiccant use and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.