Description

Piperazine, 1-[[(2R)-Tetrahydro-2-Furanyl]Methyl]- (9Ci) is a chiral piperazine derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs), particularly those requiring specific stereochemistry. Pharmaceutical research and fine chemical manufacturers need this specialized intermediate to create novel therapeutic agents with precise biological activity.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in central nervous system (CNS) and antiviral drug research.
• Asymmetric Synthesis: Utilized in the preparation of complex molecules where the (2R)-tetrahydrofuran moiety is essential for biological targeting and efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in enantioselective transformations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the development of preclinical drug candidates.
• Fine Chemical Synthesis: Used in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value nitrogen-containing compounds.

Basic Information

Product Name	Piperazine, 1-[[(2R)-Tetrahydro-2-Furanyl]Methyl]- (9Ci)
CAS No.	832698-69-8
Molecular Formula	C9H18N2O
Molecular Weight	170.25 g/mol
Synonyms	1-[(2R)-Tetrahydrofuran-2-ylmethyl]piperazine; (R)-1-(Tetrahydrofuran-2-ylmethyl)piperazine; (R)-Tetrahydrofurfuryl piperazine; 1-((R)-Tetrahydrofurfuryl)piperazine; 1-[(2R)-Oxolan-2-ylmethyl]piperazine; (R)-N-(Tetrahydrofuran-2-ylmethyl)piperazine; 832698-69-8; (R)-Tetrahydropyran-2-ylmethyl piperazine (related structure)
EINECS	Contact for details

Quality Control

Our Piperazine, 1-[[(2R)-Tetrahydro-2-Furanyl]Methyl]- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.