Description

(R)-1-Benzyl-3-Phenylpiperazine is a chiral piperazine derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a versatile and high-value chiral building block for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly those targeting neurological and psychiatric disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel central nervous system (CNS) active drugs, including potential antidepressants and antipsychotics.
• Asymmetric Synthesis: Employed as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and for creating focused libraries of bioactive molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological pathways and receptor interactions.

Basic Information

Product Name	(R)-1-Benzyl-3-Phenylpiperazine
CAS No.	832155-10-9
Molecular Formula	C₁₇H₂₀N₂
Molecular Weight	252.36 g/mol
Synonyms	(R)-1-Benzyl-3-phenylpiperazine; (R)-N-Benzyl-3-phenylpiperazine; (R)-1-Benzyl-3-phenyl-piperazine; (R)-BPP; (R)-1-Bzl-3-Ph-Pip; (3R)-1-Benzyl-3-phenylpiperazine; (R)-(-)-1-Benzyl-3-phenylpiperazine
EINECS	Contact for details

Quality Control

Our (R)-1-Benzyl-3-Phenylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and chiral excess is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.